This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GBA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 593-623 amino acids from the Central region of human GBA2.
GBA2
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target
GBA2
(Glucosidase, beta (Bile Acid) 2 (GBA2))
Alternative Name
GBA2
Background
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.