GBA2 antibody (AA 50-130)

Catalog No. ABIN7215076

This Rabbit Polyclonal antibody specifically detects GBA2 in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for GBA2 antibody (AA 50-130) (ABIN7215076)

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GBA2 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-Glucosidase IIβ Polyclonal Antibody

Specificity: Glucosidase IIβ Polyclonal Antibody detects endogenous levels of Glucosidase IIβ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Glucosidase IIbeta at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GBA2

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Alternative Name: Glucosidase IIbeta

Background: PRKCSH, G19P1, Glucosidase 2 subunit beta, 80K-H protein, Glucosidase II subunit beta, Protein kinase C substrate 60.1 kDa protein heavy chain, PKCSHPRKCSH encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. Glucosidase 2 subunit beta is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in PRKCSH have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

Molecular Weight: 59kD

Gene ID: 5589

UniProt: P14314