DNAJC3 antibody (AA 189-223)
Quick Overview for DNAJC3 antibody (AA 189-223) (ABIN6243640)
Target
See all DNAJC3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 189-223
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Predicted Reactivity
- Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This DNAJC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 189-223 amino acids of human DNAJC3.
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Isotype
- IgG
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Application Notes
- WB: 1:2000. FC: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
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Alternative Name
- DNAJC3
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Background
- Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
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Molecular Weight
- 57580
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UniProt
- Q13217
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Pathways
- ER-Nucleus Signaling
Target
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