REG3g antibody

Catalog No. ABIN6243770

This Mouse Monoclonal antibody specifically detects REG3g in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for REG3g antibody (ABIN6243770)

Target: REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This REG3g antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1790CT313-66-2

Product Details anti-REG3g Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This REG3G antibody is generated from a mouse immunized with a recombinant protein of human REG3G.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for REG3g

Target: REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))

Alternative Name: REG3G

Background: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.

Molecular Weight: 19330

UniProt: Q6UW15

Pathways: Activation of Innate immune Response