PHC1 antibody (AA 308-342)
Quick Overview for PHC1 antibody (AA 308-342) (ABIN6244140)
Target
See all PHC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 308-342
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Predicted Reactivity
- M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This PHC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-342 amino acids from human PHC1.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- PHC1 (Polyhomeotic-Like 1 (PHC1))
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Alternative Name
- PHC1
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Background
- Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.
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Molecular Weight
- 105534
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UniProt
- P78364
Target
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