SH3PXD2B antibody (AA 596-628)

Catalog No. ABIN6244202

This Rabbit Polyclonal antibody specifically detects SH3PXD2B in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for SH3PXD2B antibody (AA 596-628) (ABIN6244202)

Target: SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3PXD2B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB55314

Product Details anti-SH3PXD2B Antibody

Binding Specificity: AA 596-628

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 596-628 amino acids from human SH3PXD2B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SH3PXD2B

Target: SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))

Alternative Name: SH3PXD2B

Background: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).

Molecular Weight: 101579

UniProt: A1X283

Pathways: Positive Regulation of fat Cell Differentiation