AMPD3 antibody

Catalog No. ABIN6251794

The Mouse Monoclonal anti-AMPD3 antibody has been validated for IF, ICC and IHC (p). It is suitable to detect AMPD3 in samples from Human.

Quick Overview for AMPD3 antibody (ABIN6251794)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMPD3 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ETAD3-1

Product Details anti-AMPD3 Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Immunofluorescence: 0.5-1 μg/mL

Immunocytochemistry: 1-2 μg/mL for 30 min at RT

Immunohistology (FFPE): 2-4 μg/mL for 30 min at RT (1)

Prediluted format : incubate for 30 min at RT (2)

Optimal dilution of the AMPD3 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Alternative Name: AMPD3

Background: AMPD3 is a member of the AMP deaminase gene family. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in the gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. [RefSeq]

Gene ID: 272

UniProt: Q01432