Lambda-IgLC antibody

Catalog No. ABIN6252217

The Mouse Monoclonal anti-Lambda-IgLC antibody is suitable to detect Lambda-IgLC in samples from Human. It has been validated for FACS, WB, IHC and IF.

Quick Overview for Lambda-IgLC antibody (ABIN6252217)

Target: Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lambda-IgLC antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: LLC-1738

Product Details anti-Lambda-IgLC Antibody

Purification: Protein G affinity chromatography

Immunogen: Purified human lambda light chain was used as the immunogen for this Lambda Light Chain antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 1-2 μg/mL

Western blot: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT

The optimal dilution of the Lambda Light Chain antibody for each application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for Lambda-IgLC

Target: Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Alternative Name: Lambda Light Chain

Background: This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene ID: 28820

UniProt: P01701, P01842