IFNA2 antibody

Catalog No. ABIN6252255

This Mouse Monoclonal antibody specifically detects IFNA2 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for IFNA2 antibody (ABIN6252255)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: N39

Product Details anti-IFNA2 Antibody

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.

Isotype: IgG kappa

Application Details

Application Notes: ELISA: order BSA/azide-free format for coating

Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Alternative Name: Interferon alpha 2

Background: Recognizes a protein of 16-27  kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Gene ID: 3440

UniProt: P01563

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C