Provided assay concentrations are suggestions only, FABP7 antibody titration may be required for optimal results.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target
FABP7
(Fatty Acid Binding Protein 7, Brain (FABP7))
Alternative Name
FABP7
Background
Fatty acid binding proteins (FABPs) are proteins that bind long-chain fatty acids and are thought to be involved in fatty acid uptake, transport, and metabolism. FABP7, also known as Brain lipid binding protein or BLBP, is essential for fetal brain development, and has been found to be important in brain and breast cancer, with opposing prognoses. It is a glioblastoma stem cell marker, highly expressed in the astrocyte-derived tumor cells and an indicator of poor prognosis. Abundant expression in basal-like/triple negative (ER-, PR-, HER2-) breast cancer cells, particularly with only nuclear expression, indicates a positive prognosis.