beta Catenin antibody (C-Term)
Quick Overview for beta Catenin antibody (C-Term) (ABIN6252632)
Target
See all beta Catenin (CATNB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- C-Term
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Purification
- Protein G affinity chromatography
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Immunogen
- A C-terminal 100 amino acid segment from chicken beta-Catenin was used as the immunogen for the Beta Catenin antibody.
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Isotype
- IgG1 kappa
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Application Notes
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL
Optimal dilution of the Beta Catenin antibody to be determined by the researcher. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Alternative Name
- Beta Catenin
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Background
- Beta Catenin is a dual function protein, regulating the coordination of cell-cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. Beta catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. Beta-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]
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Gene ID
- 1499
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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