HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN6252708)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Protein G affinity chromatography
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Immunogen
- Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
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Isotype
- IgG2a kappa
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Application Notes
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Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Optimal dilution of the HLA-ABC antibody should be determined by the researcher. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- HLA-ABC
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Alternative Name
- HLA-ABC
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Background
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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UniProt
- P01889, P30443, P30499
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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