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HLA-ABC antibody

This Mouse Monoclonal antibody specifically detects HLA-ABC in FACS, IF and WB. It exhibits reactivity toward Human, Mouse and Non-Human Primate.
Catalog No. ABIN6252708

Quick Overview for HLA-ABC antibody (ABIN6252708)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

  • 69
  • 28
  • 19
  • 17
  • 15
  • 13
  • 13
  • 12
  • 11
  • 11
  • 7
  • 7
  • 6
  • 5
  • 2
  • 1
Human, Mouse, Non-Human Primate

Host

  • 55
  • 10
  • 4
Mouse

Clonality

  • 59
  • 9
Monoclonal

Conjugate

  • 28
  • 8
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HLA-ABC antibody is un-conjugated

Application

  • 52
  • 18
  • 17
  • 13
  • 10
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Clone

246-B8-E7
  • Purification

    Protein G affinity chromatography

    Immunogen

    Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

    Isotype

    IgG2a kappa
  • Application Notes

    Western blot: 1-2 μg/mL

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.2 mg/mL

    Buffer

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target

    HLA-ABC

    Alternative Name

    HLA-ABC

    Background

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889, P30443, P30499

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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