RPS6KB1 antibody (pSer398)

Catalog No. ABIN6254044

This anti-RPS6KB1 antibody is a Rabbit Polyclonal antibody detecting RPS6KB1 in WB and ELISA. Suitable for Drosophila melanogaster.

Quick Overview for RPS6KB1 antibody (pSer398) (ABIN6254044)

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Reactivity: Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RPS6KB1 Antibody

Binding Specificity: pSer398

Specificity: Specific for endogenous levels of the ~70 kDa p70 S6K protein phosphorylated at Thr398. Immunolabeling is blocked by preadsorption with the Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Cross-Reactivity: Drosophila melanogaster

Characteristics: Our p70 S6 Kinase (Ser398) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects p70 S6 Kinase (Ser398) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr398 of Drosophila p70 S6K protein, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

Target Details for RPS6KB1

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name: S6K

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 2 antibody, EC 2.7.11.1 antibody, KS6B2_HUMAN antibody, p70 beta antibody, p70 ribosomal S6 kinase beta antibody, p70 S6 kinase beta antibody, p70 S6K-beta antibody, p70 S6KB antibody, p70 S6Kbeta antibody, p70(S6K) beta antibody, p70-beta antibody, p70-S6K 2 antibody, P70S6K2 antibody, p70S6Kb antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 2 antibody, Ribosomal protein S6 kinase B2 antibody, Ribosomal protein S6 kinase beta 2 antibody, Ribosomal protein S6 kinase beta-2 antibody, Rps6kb2 antibody, S6 kinase related kinase antibody, S6 kinase-related kinase antibody, S6K beta 2 antibody, S6K beta antibody, S6K-beta antibody, S6K-beta-2 antibody, S6K2 antibody, Serine/threonine protein kinase 14 beta antibody, Serine/threonine-protein kinase 14B antibody, SRK antibody, STK14B antibody

Description Logic: Our p70 S6 Kinase (Ser398) rabbit polyclonal phosphospecific primary antibody is produced . It detects p70 S6 Kinase (Ser398) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: S6K

Molecular Weight: 70 kDa

UniProt: H1ZYE3

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect