IL-10 antibody

Catalog No. ABIN6254177

The Goat Polyclonal anti-IL-10 antibody is suitable to detect IL-10 in samples from Human, Mouse, Rat, Cow, Pig, Rabbit, Horse, Dog, Monkey, Goat, Chicken, Sheep, Hamster, Avian, Cat, Donkey and Guinea Pig. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for IL-10 antibody (ABIN6254177)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Horse, Dog, Monkey, Goat, Chicken, Sheep, Hamster, Avian, Cat, Donkey, Guinea Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This IL-10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IL-10 Antibody

Purpose: anti-IL10

Sequence: MHSSALLCCL VLLTGVRASP GQGTQSENSC THFPGNLPNM LRDLRDAFSR VKTFFQMKDQ LDNLLLKESL LEDFKGYLGC QALSEMIQFY LEEVMPQAEN QDPDIKAHVN SLGENLKTLR LRLRRCHRFL PCENKSKAVE QVKNAFNKLQ EKGIYKAMSE FDIFINYIEA YMTMKIRN

Specificity: Detects endogenous levels of total IL10 by Western blot in whole cell and tissue lysates.

Characteristics: Interleukin 10

Purification: Epitope affinity purified

Immunogen: Purified recombinant human IL10 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:250-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL10

Background:

Goat polyclonal to IL10. IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. It is involved in inflammation and immunoregulation. It down-regulates the expression of MHC class II antigens and Th1 cytokines on macrophages. It also enhances B cell survival, proliferation, and antibody production.

CSIF, GVHDS, IL-10, interleukin 10, IL10A, TGIF antibody.

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints