RAB8B antibody (C-Term)

Catalog No. ABIN6254237

The Goat Polyclonal anti-RAB8B antibody is suitable to detect RAB8B in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat, Sheep, Monkey, Hamster, Pig, Donkey, Chicken, Cat and Avian. It has been validated for WB.

Quick Overview for RAB8B antibody (C-Term) (ABIN6254237)

Target: RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat, Sheep, Monkey, Hamster, Pig, Donkey, Chicken, Cat, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This RAB8B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB8B Antibody

Binding Specificity: C-Term

Purpose: Anti-Rab8b

Sequence: MEEHASSDVE RMILGNKCDM NDKRQVSKER GEKLAIDYGI KFLETSAKSS TNVEEAFFTL ARDIMTKLNR KMNDSNSSGA GGPVKITESR SKKTSFFRCS LL

Specificity: Detects Rab8b protein in transfected cells with GFP-Rab8b cds by Western blot. This Ab is specific for Rab8b. It does not recognize Rab8a.

Characteristics: RAB8B, member RAS oncogene family

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 107 aa to the C-terminus of mouse Rab8b produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for RAB8B

Target: RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))

Alternative Name: Rab8b

Background:

Goat polyclonal antibody to mouse Rab8. Rab8 belongs to the small GTPase superfamily, Rab family. It has cell-type specific function during the process of exocytosis and coordinates regulation of the cytoskeleton. Rab8 also appears to interface with endocytic recycling circuits. At the molecular level, this GTPase regulates both the export of vesicles from the trans-Golgi apparatus, and the directed translocation along actin filaments and microtubules.

RAB8A, RAB8B, RAS-associated protein RAB8A, ras-related protein Rab-8B, ras-related protein Rab-8A, ras-related protein Rab-8B antibody.

Pathways: Positive Regulation of Peptide Hormone Secretion, Cell-Cell Junction Organization