Histone 3 antibody (H3K18ac)
Quick Overview for Histone 3 antibody (H3K18ac) (ABIN6254860)
Target
See all Histone 3 (H3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- H3K18ac
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Purpose
- Acetyl-Histone H3 (Lys18) Antibody
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Specificity
- Acetyl-Histone H3 (Lys18) Antibody detects endogenous levels of total Histone H3 protein only when acetylated at lysine18.
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Predicted Reactivity
- Bovine
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Histone H3 around the acetylation site of Lys18.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4,50 % glycerol.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- Histone 3 (H3) (Histone H3 (H3))
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Alternative Name
- Histone H3
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Background
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
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Molecular Weight
- 15 kDa
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Gene ID
- 8, 350, 835
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UniProt
- P68431
Target
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