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Histone 3 antibody (H3K18ac)

The Rabbit Polyclonal anti-Histone 3 antibody (ABIN6254860) specifically detects Histone 3 in WB, IF, IHC and ICC. The antibody is reactive with Human, Mouse, Rat and Monkey samples.
Catalog No. ABIN6254860
$441.17
Plus shipping costs $50.00
Shipping to: United States
Delivery in 11 to 13 Business Days

Quick Overview for Histone 3 antibody (H3K18ac) (ABIN6254860)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

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Human, Mouse, Rat, Monkey

Host

  • 1542
  • 294
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  • 1
Rabbit

Clonality

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Polyclonal

Conjugate

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This Histone 3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Binding Specificity

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    H3K18ac

    Purpose

    Acetyl-Histone H3 (Lys18) Antibody

    Specificity

    Acetyl-Histone H3 (Lys18) Antibody detects endogenous levels of total Histone H3 protein only when acetylated at lysine18.

    Predicted Reactivity

    Bovine

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human Histone H3 around the acetylation site of Lys18.

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, pH 7.4,50 % glycerol.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C. Stable for 12 months from date of receipt.

    Expiry Date

    12 months
  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Background

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

    Molecular Weight

    15 kDa

    Gene ID

    8, 350, 835

    UniProt

    P68431
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