Caspase 6 antibody (Cleaved-Asp179)

Catalog No. ABIN6254879

This Rabbit Polyclonal antibody specifically detects Caspase 6 in WB, IHC, ELISA, ICC and IF. It exhibits reactivity toward Human and Rat.

Quick Overview for Caspase 6 antibody (Cleaved-Asp179) (ABIN6254879)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Caspase 6 Antibody

Binding Specificity: Cleaved-Asp179

Specificity: Cleaved-Caspase 6 (Asp179) Antibody detects endogenous levels of fragment of activated Caspase 6 resulting from cleavage adjacent to Asp179.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Caspase 6 (Cleaved-Asp179).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: CASP6

Background:

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

Gene: CASP6

Molecular Weight: 18 kDa

Gene ID: 839

UniProt: P55212

Pathways: Apoptosis, Caspase Cascade in Apoptosis