MKP1/2 (pSer296), (pSer318) antibody

Catalog No. ABIN6256252

The Rabbit Polyclonal anti-MKP1/2 antibody (ABIN6256252) specifically detects MKP1/2 in IHC, WB, IF and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MKP1/2 (pSer296), (pSer318) antibody (ABIN6256252)

Target: MKP1/2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details

Binding Specificity: pSer296, pSer318

Purpose: Phospho-MKP1/2 (Ser296/Ser318) Antibody

Specificity: Phospho-MKP-1/2 (Ser296/318) Antibody detects endogenous levels of MKP-1/2 only when phosphorylated at Serine 296/318

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human MKP1/2 around the phosphorylation site of Ser296/318.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: MKP1/2

Background:

Description: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.

Gene: DUSP1

Molecular Weight: 45kDa

Gene ID: 1843

UniProt: P28562