Glycogen Synthase 1 antibody (pSer645)

Catalog No. ABIN6256392

The Rabbit Polyclonal anti-Glycogen Synthase 1 antibody has been validated for WB, ELISA, IHC, IF and ICC. It is suitable to detect Glycogen Synthase 1 in samples from Human, Mouse and Rat.

Quick Overview for Glycogen Synthase 1 antibody (pSer645) (ABIN6256392)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: pSer645

Specificity: Phospho-Glycogen Synthase (Ser645) Antibody detects endogenous levels of Glycogen Synthase only when phosphorylated at Serine 645.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Glycogen Synthase around the phosphorylation site of Ser645.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1

Background:

Description: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Gene: GYS1

Molecular Weight: 83,89kDa

Gene ID: 2997

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process