DLG2 antibody (pTyr340)

Catalog No. ABIN6256710

The Rabbit Polyclonal anti-DLG2 antibody is suitable to detect DLG2 in samples from Human, Rat and Mouse. It has been validated for WB and IHC.

Quick Overview for DLG2 antibody (pTyr340) (ABIN6256710)

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DLG2 Antibody

Binding Specificity: pTyr340

Specificity: Phospho-PSD93 (Tyr340) Antibody detects endogenous levels of PSD93.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human PSD93 around the phosphorylation site of Tyr340.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Alternative Name: PSD93

Background:

Description: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

Gene: DLG2

Molecular Weight: 110kDa

Gene ID: 1740

UniProt: Q15700