JHD3D (N-Term) antibody

Catalog No. ABIN6256834

The Rabbit Polyclonal anti-JHD3D antibody (ABIN6256834) specifically detects JHD3D in IHC and WB. The antibody is reactive with Human and Rat samples.

Quick Overview for JHD3D (N-Term) antibody (ABIN6256834)

Target: JHD3D

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: JHD3D Antibody

Specificity: JHD3D Antibody detects endogenous levels of total JHD3D.

Predicted Reactivity: Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human JHD3D, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: JHD3D

Background:

Description: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Gene: KDM4D

Molecular Weight: 52 kDa

Gene ID: 55693

UniProt: Q6B0I6