Septin 7 antibody (C-Term)

Catalog No. ABIN6257067

Product Details anti-Septin 7 Antibody

Target: Septin 7 (SEPT7)

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SEPT7 Antibody detects endogenous levels of total SEPT7.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SEPT7, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Septin 7

Target: Septin 7 (SEPT7)

Alternative Name: SEPT7 (SEPT7 Products)

Synonyms: cdc10 antibody, wu:fb38h06 antibody, zgc:56383 antibody, Septin-7 antibody, CDC10 antibody, CDC3 antibody, NBLA02942 antibody, SEPT7A antibody, Cdc10 antibody, E430034N22 antibody, septin 7a antibody, septin 7 antibody, septin 7 L homeolog antibody, sept7a antibody, SEPT7 antibody, sept7.L antibody, sept7 antibody, Sept7 antibody

Background:

Description: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).

Gene: 7-Sep

Molecular Weight: 48 kDa

Gene ID: 989

UniProt: Q16181