Fibulin 5 antibody (C-Term)

Catalog No. ABIN6257193

The Rabbit Polyclonal anti-Fibulin 5 antibody has been validated for WB, IHC, ELISA, ICC and IF. It is suitable to detect Fibulin 5 in samples from Human, Mouse and Rat.

Quick Overview for Fibulin 5 antibody (C-Term) (ABIN6257193)

Target: Fibulin 5 (FBLN5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Fibulin 5 Antibody

Binding Specificity: C-Term

Specificity: FBLN5 Antibody detects endogenous levels of total FBLN5.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FBLN5, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: FBLN5

Background:

Description: Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).

Gene: FBLN5

Molecular Weight: 50 kDa

Gene ID: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome