MEOX2 antibody (Internal Region)

Catalog No. ABIN6257271

The Rabbit Polyclonal anti-MEOX2 antibody is suitable to detect MEOX2 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, IF and ICC.

Quick Overview for MEOX2 antibody (Internal Region) (ABIN6257271)

Target: MEOX2 (Mesenchyme Homeobox 2 (MEOX2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-MEOX2 Antibody

Binding Specificity: Internal Region

Purpose: MEOX2 Antibody

Specificity: MEOX2 Antibody detects endogenous levels of total MEOX2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MEOX2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MEOX2

Target: MEOX2 (Mesenchyme Homeobox 2 (MEOX2))

Alternative Name: MEOX2

Background:

Description: Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Gene: MEOX2

Molecular Weight: 33 kDa

Gene ID: 4223

UniProt: P50222