IQCB1 antibody (Internal Region)

Catalog No. ABIN6257282

This Rabbit Polyclonal antibody specifically detects IQCB1 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for IQCB1 antibody (Internal Region) (ABIN6257282)

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-IQCB1 Antibody

Binding Specificity: Internal Region

Purpose: IQCB1 Antibody

Specificity: IQCB1 Antibody detects endogenous levels of total IQCB1.

Predicted Reactivity: Mouse,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IQCB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1

Background:

Description: Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655).

Gene: IQCB1

Molecular Weight: 69 kDa

Gene ID: 9657

UniProt: Q15051