TAO Kinase 3 antibody (Internal Region)

Catalog No. ABIN6257296

The Rabbit Polyclonal anti-TAO Kinase 3 antibody (ABIN6257296) specifically detects TAO Kinase 3 in WB, IHC, IF and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TAO Kinase 3 antibody (Internal Region) (ABIN6257296)

Target: TAO Kinase 3 (TAOK3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAO Kinase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TAO Kinase 3 Antibody

Binding Specificity: Internal Region

Purpose: TAOK3 Antibody

Specificity: TAOK3 Antibody detects endogenous levels of total TAOK3.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TAOK3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200,WB 1:500-1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TAO Kinase 3

Target: TAO Kinase 3 (TAOK3)

Alternative Name: TAOK3

Background:

Description: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

Gene: TAOK3

Molecular Weight: 110 kDa

Gene ID: 51347

UniProt: Q9H2K8