TTC19 antibody (Internal Region)

Catalog No. ABIN6257537

Product Details anti-TTC19 Antibody

Target: TTC19 (Tetratricopeptide Repeat Domain 19 (TTC19))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC19 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: TTC19 Antibody detects endogenous levels of total TTC19.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TTC19, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TTC19

Target: TTC19 (Tetratricopeptide Repeat Domain 19 (TTC19))

Alternative Name: TTC19 (TTC19 Products)

Synonyms: TTC19 antibody, 2010204O13Rik antibody, 2810460C24Rik antibody, AI505442 antibody, RGD1311797 antibody, MC3DN2 antibody, si:dkey-270k22.4 antibody, tetratricopeptide repeat domain 19 antibody, TTC19 antibody, Ttc19 antibody, ttc19 antibody

Background:

Description: Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).

Gene: TTC19

Molecular Weight: 35 kDa

Gene ID: 54902

UniProt: Q6DKK2