Cyclin K antibody (N-Term)

Catalog No. ABIN6257597

This Rabbit Polyclonal antibody specifically detects Cyclin K in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Cyclin K antibody (N-Term) (ABIN6257597)

Target: Cyclin K (CCNK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin K antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Cyclin K Antibody

Binding Specificity: N-Term

Specificity: CCNK Antibody detects endogenous levels of total CCNK.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCNK, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Cyclin K

Target: Cyclin K (CCNK)

Alternative Name: CCNK

Background:

Description: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).

Gene: CCNK

Molecular Weight: ?64 kDa

Gene ID: 8812

UniProt: O75909