BMP8A antibody (Internal Region)

Catalog No. ABIN6257684

This Rabbit Polyclonal antibody specifically detects BMP8A in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for BMP8A antibody (Internal Region) (ABIN6257684)

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-BMP8A Antibody

Binding Specificity: Internal Region

Specificity: BMP8A Antibody detects endogenous levels of total BMP8A.

Predicted Reactivity: Pig,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BMP8A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for BMP8A

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Alternative Name: BMP8A

Background:

Description: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.

Gene: BMP8A

Molecular Weight: 45 kDa

Gene ID: 353500

UniProt: Q7Z5Y6

Pathways: Negative Regulation of Hormone Secretion