NUTF2 antibody (Internal Region)

Catalog No. ABIN6257795

This Rabbit Polyclonal antibody specifically detects NUTF2 in IHC, WB, ELISA, IF and ICC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NUTF2 antibody (Internal Region) (ABIN6257795)

Target: NUTF2 (Nuclear Transport Factor 2 (NUTF2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUTF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-NUTF2 Antibody

Binding Specificity: Internal Region

Specificity: NUTF2 Antibody detects endogenous levels of total NUTF2.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NUTF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NUTF2

Target: NUTF2 (Nuclear Transport Factor 2 (NUTF2))

Alternative Name: NUTF2

Background:

Description: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.

Gene: NUTF2

Molecular Weight: 14 kDa

Gene ID: 10204

UniProt: P61970

Pathways: Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome