POLR1C antibody (Internal Region)

Catalog No. ABIN6258123

The Rabbit Polyclonal anti-POLR1C antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect POLR1C in samples from Human and Mouse.

Quick Overview for POLR1C antibody (Internal Region) (ABIN6258123)

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-POLR1C Antibody

Binding Specificity: Internal Region

Specificity: POLR1C Antibody detects endogenous levels of total POLR1C.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human POLR1C, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for POLR1C

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Alternative Name: POLR1C

Background:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Gene: POLR1C

Molecular Weight: 39 kDa

Gene ID: 9533

UniProt: O15160