GPR75 antibody (Internal Region)

Catalog No. ABIN6258191

This Rabbit Polyclonal antibody specifically detects GPR75 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for GPR75 antibody (Internal Region) (ABIN6258191)

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR75 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GPR75 Antibody

Binding Specificity: Internal Region

Specificity: GPR75 Antibody detects endogenous levels of total GPR75.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPR75, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GPR75

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Alternative Name: GPR75

Background:

Description: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Gene: GPR75

Molecular Weight: 59 kDa

Gene ID: 10936

UniProt: O95800