MKNK1 antibody (Internal Region)

Catalog No. ABIN6258266

This Rabbit Polyclonal antibody specifically detects MKNK1 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for MKNK1 antibody (Internal Region) (ABIN6258266)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-MKNK1 Antibody

Binding Specificity: Internal Region

Specificity: Mnk1 Antibody detects endogenous levels of total Mnk1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Mnk1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MKNK1

Background:

Description: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

Gene: MKNK1

Molecular Weight: 51 kDa

Gene ID: 8569

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor