PAEP antibody

Catalog No. ABIN6258298

Product Details anti-PAEP Antibody

Target: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAEP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: PAEP antibody detects endogenous levels of total PAEP

Cross-Reactivity: Human, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PAEP

Target: PAEP (Progestagen-Associated Endometrial Protein (PAEP))

Alternative Name: PAEP (PAEP Products)

Synonyms: GD antibody, GdA antibody, GdF antibody, GdS antibody, PAEG antibody, PEP antibody, PP14 antibody, PAEP antibody, Beta-LG antibody, LGB antibody, progestagen associated endometrial protein antibody, progestagen-associated endometrial protein antibody, PAEP antibody, Paep antibody

Background:

Description: Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).

Gene: PAEP

Molecular Weight: 21 kDa

Gene ID: 5047

UniProt: P09466