NECAB3 antibody (Internal Region)

Catalog No. ABIN6258487

Product Details anti-NECAB3 Antibody

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NECAB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NECAB3 Antibody detects endogenous levels of total NECAB3.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NECAB3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NECAB3

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Alternative Name: NECAB3 (NECAB3 Products)

Synonyms: Apba2bp antibody, APBA2BP antibody, NECAB3 antibody, EFCBP3 antibody, NIP1 antibody, STIP3 antibody, SYTIP2 antibody, XB51 antibody, dJ63M2.4 antibody, dJ63M2.5 antibody, 2900010M17Rik antibody, AI853434 antibody, Nip1 antibody, N-terminal EF-hand calcium binding protein 3 antibody, Necab3 antibody, NECAB3 antibody

Background:

Description: Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions, the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.

Gene: NECAB3

Molecular Weight: 44 kDa

Gene ID: 63941

UniProt: Q96P71