CHSY1 antibody (Internal Region)

Catalog No. ABIN6259032

The Rabbit Polyclonal anti-CHSY1 antibody has been validated for WB, ELISA, IHC, ICC and IF. It is suitable to detect CHSY1 in samples from Human, Mouse and Rat.

Quick Overview for CHSY1 antibody (Internal Region) (ABIN6259032)

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CHSY1 Antibody

Binding Specificity: Internal Region

Specificity: CHSY1 Antibody detects endogenous levels of total CHSY1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CHSY1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CHSY1

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Alternative Name: CHSY1

Background:

Description: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.

Gene: CHSY1

Molecular Weight: 91 kDa

Gene ID: 22856

UniProt: Q86X52

Pathways: Glycosaminoglycan Metabolic Process