CHSY1 antibody (AA 310-390)

Catalog No. ABIN7214208

The Rabbit Polyclonal anti-CHSY1 antibody is suitable to detect CHSY1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for CHSY1 antibody (AA 310-390) (ABIN7214208)

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CHSY1 Antibody

Binding Specificity: AA 310-390

Purpose: Rabbit Anti-CHSY1 Polyclonal Antibody

Specificity: CHSY1 Polyclonal Antibody detects endogenous levels of CHSY1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CHSY1 at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHSY1

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Alternative Name: CHSY1

Background: CHSY1, CHSY, CSS1, KIAA0990, Chondroitin sulfate synthase 1, Chondroitin glucuronyltransferase 1, Chondroitin synthase 1, ChSy-1, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1, N-acetylgalactosaCHSY1 encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of CHSY1 may play a role in colorectal cancer, and mutations in CHSY1 are a cause of temtamy preaxial brachydactyly syndrome.

Molecular Weight: 91kD

Gene ID: 22856

UniProt: Q86X52

Pathways: Glycosaminoglycan Metabolic Process