PARD6B antibody (Internal Region)

Catalog No. ABIN6259145

Product Details anti-PARD6B Antibody

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD6B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PARD6B Antibody detects endogenous levels of total PARD6B.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PARD6B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PARD6B

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Alternative Name: PARD6B (PARD6B Products)

Synonyms: PARD6B antibody, AV025615 antibody, Par6b antibody, PAR6B antibody, par-6 antibody, par6 antibody, pard6beta antibody, si:dkey-192i18.6 antibody, PAR-6 antibody, PAR-6B antibody, par-6 family cell polarity regulator beta antibody, par-6 family cell polarity regulator beta S homeolog antibody, par-6 partitioning defective 6 homolog beta (C. elegans) antibody, PARD6B antibody, Pard6b antibody, pard6b.S antibody, pard6b antibody

Background:

Description: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Gene: PARD6B

Molecular Weight: 38 kDa

Gene ID: 84612

UniProt: Q9BYG5

Pathways: Cell-Cell Junction Organization