SF3B4 antibody (N-Term)
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- Target See all SF3B4 Antibodies
- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SF3B4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- SF3B4 Antibody detects endogenous levels of total SF3B4.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SF3B4, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (AA 13-122) antibody
SF3B4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1B8 unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (Internal Region) antibodySF3B4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (AA 158-187) antibodySF3B4 Reactivity: Human WB Host: Rabbit Polyclonal RB40410 unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (N-Term) antibodySF3B4 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Pig, Rabbit, Guinea Pig, Horse, Chicken, Bat, Hamster, Monkey, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) antibodySF3B4 Reactivity: Human WB, IF, ICC, IHC (p) Host: Mouse Monoclonal 3A1 unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (Internal Region) antibodySF3B4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (N-Term) antibodyVerified SF3B4 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (AA 151-200) antibodySF3B4 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Pig, Rabbit, Guinea Pig, Horse, Chicken, Bat, Hamster, Monkey, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) (AA 1-200) antibodySF3B4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) antibodySF3B4 Reactivity: Human, Mouse, Rat, Cow, Pig, Mammalian WB, IHC, IF, ICC Host: Mouse Monoclonal 3A1 unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
- Alternative Name
- SF3B4 (SF3B4 Products)
- Background
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Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).
Gene: SF3B4
- Molecular Weight
- 55 kDa
- Gene ID
- 10262
- UniProt
- Q15427
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