SRCIN1 antibody (Internal Region)

Catalog No. ABIN6259194

The Rabbit Polyclonal anti-SRCIN1 antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect SRCIN1 in samples from Human, Mouse and Rat.

Quick Overview for SRCIN1 antibody (Internal Region) (ABIN6259194)

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRCIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SRCIN1 Antibody

Binding Specificity: Internal Region

Specificity: SNIP Antibody detects endogenous levels of total SNIP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SNIP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SRCIN1

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Alternative Name: SRCIN1

Background:

Description: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Gene: SRCIN1

Molecular Weight: 112 kDa

Gene ID: 80725

UniProt: Q9C0H9