TMEM30B antibody (Internal Region)

Catalog No. ABIN6259263

The Rabbit Polyclonal anti-TMEM30B antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect TMEM30B in samples from Human and Mouse.

Quick Overview for TMEM30B antibody (Internal Region) (ABIN6259263)

Target: TMEM30B (Transmembrane Protein 30B (TMEM30B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM30B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-TMEM30B Antibody

Binding Specificity: Internal Region

Specificity: TMEM30B Antibody detects endogenous levels of total TMEM30B.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TMEM30B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TMEM30B

Target: TMEM30B (Transmembrane Protein 30B (TMEM30B))

Alternative Name: TMEM30B

Background:

Description: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.

Gene: TMEM30B

Molecular Weight: 38 kDa

Gene ID: 161291

UniProt: Q3MIR4