RPAP2 antibody (Internal Region)

Catalog No. ABIN6259467

The Rabbit Polyclonal anti-RPAP2 antibody is suitable to detect RPAP2 in samples from Human, Mouse and Rat. It has been validated for WB, IF and ICC.

Quick Overview for RPAP2 antibody (Internal Region) (ABIN6259467)

Target: RPAP2 (RNA Polymerase II Associated Protein 2 (RPAP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-RPAP2 Antibody

Binding Specificity: Internal Region

Purpose: RPAP2 Antibody

Specificity: RPAP2 Antibody detects endogenous levels of total RPAP2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPAP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RPAP2

Target: RPAP2 (RNA Polymerase II Associated Protein 2 (RPAP2))

Alternative Name: RPAP2

Background:

Description: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

Gene: RPAP2

Molecular Weight: 70 kDa

Gene ID: 79871

UniProt: Q8IXW5