SRRM1 antibody (C-Term)

Catalog No. ABIN6259480

Product Details anti-SRRM1 Antibody

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Binding Specificity: C-Term

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: SRRM1 Antibody detects endogenous levels of total SRRM1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SRRM1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Alternative Name: SRRM1 (SRRM1 Products)

Synonyms: 160-KD antibody, POP101 antibody, SRM160 antibody, AA407769 antibody, Srm160 antibody, serine and arginine repetitive matrix 1 antibody, serine/arginine repetitive matrix 1 antibody, SRRM1 antibody, Srrm1 antibody

Background:

Description: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Gene: SRRM1

Molecular Weight: 102 kDa

Gene ID: 10250

UniProt: Q8IYB3