AZI2 antibody (N-Term)

Catalog No. ABIN6259485

The Rabbit Polyclonal anti-AZI2 antibody has been validated for ELISA, WB, IF and ICC. It is suitable to detect AZI2 in samples from Human, Rat and Mouse.

Quick Overview for AZI2 antibody (N-Term) (ABIN6259485)

Target: AZI2 (5-Azacytidine Induced 2 (AZI2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AZI2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-AZI2 Antibody

Binding Specificity: N-Term

Specificity: AZI2 Antibody detects endogenous levels of total AZI2.

Predicted Reactivity: Pig

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AZI2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AZI2

Target: AZI2 (5-Azacytidine Induced 2 (AZI2))

Alternative Name: AZI2

Background:

Description: Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

Gene: AZI2

Molecular Weight: 48 kDa

Gene ID: 64343

UniProt: Q9H6S1