AGXT2 antibody (Internal Region)

Catalog No. ABIN6259832

This Rabbit Polyclonal antibody specifically detects AGXT2 in WB, IHC, ELISA, ICC, IF and IHC (fro). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AGXT2 antibody (Internal Region) (ABIN6259832)

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AGXT2 Antibody

Binding Specificity: Internal Region

Specificity: AGXT2 Antibody detects endogenous levels of total AGXT2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AGXT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Alternative Name: AGXT2

Background:

Description: Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.

Gene: AGXT2

Molecular Weight: 57 kDa

Gene ID: 64902

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process