AP3B1 antibody (C-Term)

Catalog No. ABIN6259966

This anti-AP3B1 antibody is a Rabbit Polyclonal antibody detecting AP3B1 in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for AP3B1 antibody (C-Term) (ABIN6259966)

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AP3B1 Antibody

Binding Specificity: C-Term

Specificity: AP3B1 Antibody detects endogenous levels of total AP3B1.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AP3B1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AP3B1

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Alternative Name: AP3B1

Background:

Description: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Gene: AP3B1

Molecular Weight: 140 kDa

Gene ID: 8546

UniProt: O00203

Pathways: SARS-CoV-2 Protein Interactome