CDC23 antibody (Internal Region)

Catalog No. ABIN6259975

The Rabbit Polyclonal anti-CDC23 antibody (ABIN6259975) specifically detects CDC23 in WB, ELISA, ICC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for CDC23 antibody (Internal Region) (ABIN6259975)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CDC23 Antibody

Binding Specificity: Internal Region

Specificity: APC8 Antibody detects endogenous levels of total APC8.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APC8, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: CDC23

Background:

Description: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Gene: CDC23

Molecular Weight: 68 kDa

Gene ID: 8697

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus