ARMCX3 antibody (N-Term)

Catalog No. ABIN6260044

Product Details anti-ARMCX3 Antibody

Target: ARMCX3 (Armadillo Repeat Containing, X-Linked 3 (ARMCX3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARMCX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ARMX3 Antibody detects endogenous levels of total ARMX3.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARMX3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ARMCX3

Target: ARMCX3 (Armadillo Repeat Containing, X-Linked 3 (ARMCX3))

Alternative Name: ARMCX3 (ARMCX3 Products)

Synonyms: ALEX3 antibody, dJ545K15.2 antibody, 1200004E24Rik antibody, AI450003 antibody, ARMCX3 antibody, DKFZp459E2029 antibody, armadillo repeat containing, X-linked 3 antibody, ARMCX3 antibody, Armcx3 antibody

Background:

Description: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.

Gene: ARMCX3

Molecular Weight: 38kDa

Gene ID: 51566

UniProt: Q9UH62