ARRDC4 antibody (Internal Region)

Catalog No. ABIN6260056

Product Details anti-ARRDC4 Antibody

Target: ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARRDC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Arrdc4 Antibody detects endogenous levels of total Arrdc4.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Arrdc4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ARRDC4

Target: ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))

Alternative Name: ARRDC4 (ARRDC4 Products)

Synonyms: ARRDC4 antibody, ARRDC3 antibody, LRRG00117 antibody, 2410003C09Rik antibody, AV216361 antibody, arrestin domain containing 4 antibody, ARRDC4 antibody, CpipJ_CPIJ008372 antibody, arrdc4 antibody, Arrdc4 antibody

Background:

Description: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake (PubMed:19605364).

Gene: ARRDC4

Molecular Weight: 45kDa

Gene ID: 91947

UniProt: Q8NCT1