C19orf10 antibody (Internal Region)

Catalog No. ABIN6260360

This Rabbit Polyclonal antibody specifically detects C19orf10 in WB and IHC. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for C19orf10 antibody (Internal Region) (ABIN6260360)

Target: C19orf10 (Chromosome 19 Open Reading Frame 10 (C19orf10))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C19orf10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-C19orf10 Antibody

Binding Specificity: Internal Region

Purpose: C19orf10 Antibody

Specificity: C19orf10 Antibody detects endogenous levels of total C19orf10

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human C19orf10, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for C19orf10

Target: C19orf10 (Chromosome 19 Open Reading Frame 10 (C19orf10))

Alternative Name: C19orf10

Background:

Description: Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).

Gene: MYDGF

Molecular Weight: 19kDa

Gene ID: 56005

UniProt: Q969H8

Pathways: ER-Nucleus Signaling